Chemical Genomics Facility

Overview of Services

The Chemical Genomics Facility (CGF) is a newly established facility at the Purdue Insitute for Drug Discovery. The mission of the CGF is to provide expertise and resources to investigators from Purdue and others to access to the state-of-the-art technologies and instrumentation in high throughput screen (HTS) and high content screen (HCS) to facilitate the identification of chemical and genomic tools to study biological pathways and the discover of lead agents for the development of novel therapeutics an ddiagnostic approaches. The faicility provides provides services through all stages of a screening campaign, from assay development through data analysis. These services include the following:

 

• Consultation and assistance in assay development, implementation, validation and miniaturization specific to the target of interest;
• Chemical libraries including diverse drug-like small molecules, targeted libraries, fragment libraries, natural products and their derivatives, and known drugs and bioactives, all pre-plated and ready to screen;
• Instrumentation for HTS and HCS, including liquid handling robots, plate readers, automated imager and image analysis platform;
• Assistance with dose-dependence determination and analysis of biomolecular interactions (hit confirmation and validation);
• Assistance with data analysis and structure search will be provided as needed.

 

Leadership

Director


Zhong-Yin Zhang, Collaboration
zhang-zy@purdue.edu
765-496-7749

Core Staff:

Lan Chen, Operation
lanchen@purdue.edu
765-496-6668

 

Li Wu, Operation
lw@purdue.edu

 

Location and hours of operation

Hours      Location

Monday - Friday
9 am - 5 pm 

     Discovery Park
     720 Clinic Drive
     West Lafayette, IN  47907
     DRUG B047

Getting Started

**For Purdue individuals: First-time users should click "Sign-up" in upper right.  Returning students will click "Login"

**For Non-Purdue individuals: Before you register, you must be assigned a Business Partner Number and given Purdue credentials to register/login.  

Please contact the center manager for further information.

 

Links and Resources

  1. Purdue Institution for Drug Discovery

Contacts

Name Role Phone Email Location
Lan Chen
Operations
 
765-496-6668
 
lanchen@purdue.edu
 
DRUG B047
 
Li Wu
Operations
 

 
lw@purdue.edu
 
DRUG B047
 
Zhong-Yin Zhang
Chemical Genomics Director
 
765-496-7749
 
zhang-zy@purdue.edu
 

 

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