Purdue Center for Macromolecular Crystallography

Overview of Services

The Macromolecular Crystallography X-ray Diffraction Lab is used by researchers to collect their own X-ray data in order to determine the molecular structures of proteins, viruses, and nucleic acids using X-ray crystallographic techniques. The new "curly" is a modern Rigaku X-ray MicroMax-007 HF generator, with VariMax-VHF Arc)Sec confocal optics (X-ray beam about 100 times stronger, and only 100 microns, instead of 500 microns), and an Eiger2 R 4M photon counting detector (instead of a charge integrating image plate detector).  The old "moe" was decommissioned July 24, 2023.  It was a Rigaku RU-H2R generator, with a Rigaku R-AXIS IV++ image plate detector, multilayer confocal X-ray focusing optics, Oxford Cryosystems dry nitrogen gas cryogenic crystal cooler, and an inverted phi axis for easy mounting and recovery of crystals. 

Getting Started

Contact the X-ray Diffraction Lab manager Tim Schmidt (tschmidt@purdue.edu) for initial X-ray safety training and subsequent help using the equipment to collect X-ray data. For those with little or no background in X-ray crystallography, assistance in understanding the basic fundamentals of X-ray crystallography is also provided.

Leadership

Professors John Tesmer, Nick Noinaj - Directors

  

Tim Schmidt - X-Ray Lab Manager

765-496-3131

tschmidt@purdue.edu

Location

   

 

Hockmeyer Hall of Structural Biology

Room 289

240 South Martin Jischke Drive

West Lafayette, IN  47907

iLab

**For Purdue individuals: First-time users should click "Sign-up" in upper right.  Returning students will click "Login"

 

**For Non-Purdue individuals: Before you register, you must be assigned a Business Partner Number and given Purdue credentials to register/login.  

Please contact the center manager for further information.

Rates

moe was decommissioned July 24, 2023

For moe, $45 per day for Purdue Cancer Center Research members, or $11.25 for less than 6 hours.

For moe, $133 per day for non-PCCR members, or $33.25 for less than 6 hours.

 

For the new curly, $100 per day for PCCR members, or $75 for less than 6 hours.

For the new curly, $133 per day for non-PCCR members, or $100 for less than 6 hours.

 

 

 

Contacts

Name Role Phone Email Location
Tim Schmidt
X-Ray Lab Manager
 
765-496-3131
 
tschmidt@purdue.edu
 
Hock 320